Epidemiological Assessment of the Burden and Determinants of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Wounds
Abstract
Background and Objectives: One important pathogen linked to healthcare is Methicillin-resistant Staphylococcus aureus (MRSA), which is known to cause wound infections that have higher rates of morbidity and death.
The purpose of this study is to ascertain the frequency of Methicillin-Resistant Staphylococcus aureus (MRSA) and to identify the risk factors linked to patient wound infections.
Material and methods:Methicillin-resistant Staphylococcus aureus isolated from wound infections was studied using the cross-sectional study to assess its antibiotic resistance pattern and risk factors. All patients who were suspected of having wound infections and had not taken antibiotics in the two weeks before the study period was included in the present study. The research study had 100 participants in total. Utilizing a structured questionnaire, information about sociodemographic traits and the risk factors associated with them was acquired.
Results: Among a group of 100 patients who were suspected of developing wound infection, 45 of them (45%) were found to have S. aureus wound infections based on culture confirmation. Out of them, 9 (20%) were MRSA. The study population had an overall prevalence rate of 9% for MRSA, with 9 out of 100 individuals affected. Out of the 20 patients who were admitted to the hospital and the 80 patients who were treated as outpatients and suspected of having a wound infection, 55.0% (11 out of 20) and 31.3% (25 out of 80) were found to have a positive culture for S. aureus, respectively.The total incidence of Methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients was 10.0% (2 out of 20), whereas in non-hospitalized patients it was 8.8% (7 out of 80).
Conclusion: Among the 100 patients who were suspected to have wound infection, 45 of them, which are45% of the total, were confirmed to have S. aureus by culture testing. Out of them, 9 (20%) were MRSA. Wound infection caused by MRSA had a significant correlation with profession and being diagnosed in the inpatient department. More than 50% of MRSA isolates exhibited resistance to gentamicin, ciprofloxacin, cotrimoxazole, and erythromycin.
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