Influence of Craterispermum schweinfurthi leaf extract on glucose homeostasis in male Wistar rats

Saronee F, Okari K, Nwikue G, Dimkpa VO, Ante IA — Tue, 12 Aug 2025 00:00:00 +0000

The present study aims to determine the potential influence of Craterispermum schweinfurthi leaf extract on glucose homeostasis using male Wistar rats as models. 48male Wistar rats were acclimatized and subsequently randomly divided into 6 groups of 8 rats each. Diabetes was induced in all rat groups except Group 1 using alloxan at a dose of 200mg/kg bw administered intraperitonially. Diabetes was confirmed after 72 hours of alloxan administration if the blood glucose level is ≥ 11.1 mmol/L (200mg/dl) and was daily treated with different concentrations of extract.Compared to group 2 (Untreated Diabetic) rats, administration of graded doses ofthe extract of Craterispermum schweinfurthi amongstGroups 3, 4 and 5 rats demonstrated a dose dependent significant reduction (p<0.05)in blood glucose level and glycosylated hemoglobin concentrationwith the highest dose demonstrating the most impactful outcome. Suggesting a possible hypoglycemic and anti-hyperglycemic effects of the extract. Similar results were observed amongst group 6rats followingadministration of Glibenclamide. Treatment of diabetic rats with hydromethanol leaf extract of Craterispermum schweinfurthi lowered blood glucose level and ameliorated glycosylated hemoglobin concentration in male Wistar rats.

Eating Behaviors of Early Childhood at a Selected Upazila in Bangladesh

Mariam Akter, Tumpa Gharami, Halima Akter — Mon, 25 Aug 2025 09:49:54 +0000

Background: Eating behavior plays a vital role in both the prevention and management of chronic illnesses associated with poor nutrition. Children who are overweight tend to display stronger food responsiveness, derive more enjoyment from eating, and often consume more food in response to emotional cues. The aim of this study was to assess eating behaviors among young children in a selected Upazila of Bangladesh.

Methods: This cross-sectional study included a total of 103 mothers with children aged between 1 and 5 years. Participants were chosen using a convenience sampling method. Data were collected using a self-administered questionnaire comprising two sections: Part 1 included socio-demographic information, and Part 2 consisted of the Child Eating Behavior Questionnaire (CEBQ). Data analysis was performed using both descriptive and inferential statistics via SPSS version 26.

Results: The study found a moderate overall mean score (2.91 ± 0.33) in children's eating behaviors, with variability observed across the eight subscales of the CEBQ. The average age of participating mothers was 27.75 years (SD = 3.816). Statistically significant associations were observed between children’s eating behaviors and various socio-demographic factors, including mothers’ education level (F = 5.519, p = 0.005), fathers’ education level (F = 7.328, p = 0.000), fathers’ occupation (F = 2.687, p = 0.036), and the number of siblings (r = 0.334, p = 0.001).

Conclusion: The findings highlight meaningful associations between several demographic variables and children's eating behaviors. These results support the need for policy-level initiatives aimed at promoting food security and balanced nutrition during early childhood, with the goal of reducing malnutrition and supporting healthy development in Bangladesh.

GPH-International Journal of Health Sciences and Nursing

Influence of Craterispermum schweinfurthi leaf extract on glucose homeostasis in male Wistar rats

Eating Behaviors of Early Childhood at a Selected Upazila in Bangladesh