GPH-International Journal of Biological & Medicine Science

The Influence Of Locality On Relapse Among Schizophrenic Patients

Chinawa, Francis Chukwuemeka — 2024-03-20

This study examined the influence of locality on the relapse rate among schizophrenic patients in Federal Neuropsychiatric Hospital Enugu. 120 participants made up of 60 males and 60 females were used. The 60 males comprised 30 highly educated and 30 less educated while the females were made up of 19 highly educated and 41 less educated. 52 participants were drawn from the rural residence while 68 were from the urban residence. All the participants were treated at the Federal Neuropsychiatric Hospital Enugu. The Positive and Negative Syndrome Scale (PANSS) key, Fishzbein & Oplar (2004) was used to assess the rate of relapse among the schizophrenic patients. Factorial design was used. The data collected was analysed using the One-way Analyses of variance (ANOVA). The result show significant main influence of locality on relapse, F(1, 113)=41.340, P<0.001. These results were discussed with its implication to the health of the patient, the family and society at large. Suggestions and recommendation for further studies made.

Spinal Cord Injury: Causes, types of manifestation and related complications of the patients in northern division of Bangladesh

Md. Shafiqul Islam — 2024-03-20

Background: This study explores Spinal Cord Injuries (SCI) in the Northern Division of Bangladesh, including its etiology, symptoms, and complications. The research focuses on this region to understand the etiology, varieties of SCI presentations, and the issues affected persons encounter. Purpose: to study the causes, symptoms, and complications of Spinal Cord Injuries (SCI) in Northern Bangladesh. Methods: In order to better understand Spinal Cord Injuries (SCI) among patients at Rajshahi Medical College Hospital and Rajshahi-CRP, Northern Division of Bangladesh, a quantitative cross-sectional descriptive design was used in this study. This convenience sample (n=300) includes patients who are undergoing treatment as well as those who have been discharged. Patients with SCI who have not had a head injury meet the inclusion criteria; patients who are unconscious or lack a diagnosis are not. Validated by a clinical physiotherapist, the data collection process uses semi-structured questionnaires and in-person interviews in accordance with ethical criteria that have been authorized by the ethical review board of Rajshahi Medical College. This ensures that patient care is not compromised. Results: The study had 300 participants, 80% male and 20% female, aged 20–50. About 42% were employed, mostly secondary school graduates, and rural residents. Trauma caused 64% of spinal cord injuries and paraplegia. 34% had pressure sores, while 92% had moderate discomfort. Urological and muscle problems affected 70% of patients. 68% of participants had psychological issues, including depression. Autonomic dysreflexia was 14%. Conclusion: This study illuminates the origins, symptoms, and complications of Spinal Cord Injuries (SCI) in Northern Bangladesh, providing useful insights for better management and care.

COMMON MUSCULOSKELETAL PROBLEMS ARISES AMONG WOMEN AFTER PARTURITION AT SELECTED AREA OF BANGLADESH

Mahbuba Akter — 2024-03-20

Background: Pregnancy increases the susceptibility to developing musculoskeletal diseases. Postpartum musculoskeletal issues are frequently observed after childbirth, causing significant discomfort and distress for women.

Purpose:To identify the common musculoskeletal problems that arises among women after the event of parturition at a selected area of Bangladesh.

Methods:A cross-sectional study of Dhaka hospital postpartum mothers with musculoskeletal complaints was conducted. Study sites were Enam Medical College and Super Medical Hospital. Convenience sampling yielded 112 eligible individuals. Ethics, hospital approval, and participant anonymity were crucial. Face-to-face interviews using questionnaires and VAS were used to collect data. We obtained informed consent from participants to ensure confidentiality and withdrawal. We followed WHO and Bangladesh Medical Research Council ethical guidelines to ensure research integrity.

Results:The Bangladeshi postpartum women study revealed common musculoskeletal disorders and their relationships. The majority of participants, 23–27 (55%) with one or two children, reported low back pain (57.1%), pelvic girdle discomfort (67.9%), and urine incontinence (38.4%). Pelvic girdle pain, diastasis recti, and urine incontinence were linked to childbirth. greater kids mean greater pain. The OREBRO scale showed varying severity (mean score: 101.64 ± 12.56). Childbirth affected musculoskeletal complaints, as shown by OMPQ ratings and participant age. This study prepares for more interventions.

Conclusion:The study proposes that these findings can serve as fundamental information for the development of management and assessment programs in the postpartum musculoskeletal population.

Pharmacoepidemiologic Study of the Complementary and Alternative Medicine (CAM) Use in Patient with Cancer in Benghazi, Libya

Aisha M. Alfituri — 2024-04-06

Background: Cancer patients are increasingly turning to complementary and alternative medicine (CAM) to improve their physical and psychological well-being. This study aimed to explore the prevalence of complementary and alternative medicine (CAM) use by Libyan populations in Benghazi city.

Methods: This cross-sectional survey was conducted among 100 patients attending the National Cancer Center at Howari Hospital in Benghazi city. A 16-item questionnaire was used to collect the data. The questionnaire addressed the sociodemographic characteristics, cancer conditions, and use of CAM. The main outcome of interest was “use of any CAM therapy since cancer diagnosis.”

Results: The total prevalence of CAM among cancer patients was 100%, regardless of cancer type. Lung and breast cancer were the most prevalent in our study (23 and 22%), with stage 2 being the most common cancer (47%). Prayer was the most widely used CAM modality among study participants (100%). Our data also showed that males had a higher number (57%), and the age group 40-59 was the most common. The highest percentage of participants had a diploma or bachelor degree (54%). Similarly, those living in the city had the highest rates (69%). As well, our results revealed that the most prevalent reason for using CAM was to improve sleep and reduce pain (68%).

Conclusions: This study revealed a prevalent CAM use among cancer patients in the city of Benghazi. It is necessary to promote a patient-centered approach to CAM use.

Vulvovaginal Candidiasis In Pregnant Women

Nawal Abdulwahhab Alfaytouri — 2024-04-06

This study aims to analyzing demographic data of patients,isolate and identify Candida species, which causes vaginal infections, and a study of its prevalence among pregnant women in Sorman city, Libya.210 specimens collected from patients admitted to the Maternity Care Center in the combined clinic. carried immediately to the Microbiology Laboratory in the National Cancer Institute, Subrata, Libya for direct microscopy, culturing, and characterization. Each participant was given an interview questionnaire and asked about their age, educational level, employment position, and history of recurrent vaginal yeast infection. Chronic diseases were also listed on the data collecting form.Identification of Candida species using Chrome agar: A total of 100 isolates have been recovered in this study, of which 72 isolates were obtained as pure cultures on Chrome agar medium. According to their color on Chrome agar, these 72 colonies were categorized to 5 main species namely Candida albicans, C. glabrata, C. krusei, C. parapsilosis, and C. tropicalis. Genotypic identification of Candida species in this investigation was validated by the ITS tree. Eight strains from this investigation were found in the Candida albicans clade, which had a high bootstrap value of 99 percent ML/99 percent MP. These were therefore identified as Candida albicans., Within the Candida glabrata clade, three isolates were grouped together, demonstrating a strong support value of 99% ML/99%MP. These strains were recognized as belonging to the C. glabrata species, while one isolate was recognized as belonging to the C. tropicalis species, with a high support value of 99% ML/99%MP.

Effects of Smoothies on Semen Parameters, Nitric Oxide and Total Protein in Male Wistar Rats

Gbaranor K. B. — 2024-04-24

Fruits are very important to humans and they have several essential nutrients that are important to improve their overall health. The aim of this study is to investigate the effects of smoothies (banana, apple and pineapple) on semen parameters and nitric oxide in male Wistar rats. Thirty (30) animals weighing 130kg to 180kg were randomly selected into 6 groups with 5 animals per group. Group 1 received 5mls of distilled water, group 2 received 1ml/kg (low dose) of smoothies, group 3 received 2ml/kg (medium dose), group 4 received 3ml/kg (high dose), group 5 received 400mg/kg of monosodium glutamate, group 6 received 400mg/kg of monosodium-glutamate and 3ml/kg (high dose) of smoothies co-administered. Administration was carried out for 14 days and on the 15^th day, the animals were sacrificed, semen was harvested and 5ml blood was collected via cardiac puncture. Statistical analysis was done using ANOVA and expressed as Mean±SEM. Statistically P < 0.05 was said to be significant. SPSS version 26 was used. Results from the study showed significant increase in sperm morphology and sperm volume and decrease in sperm count and sperm viability. There was significant increase in the level of nitric oxide dose-dependent and thus could aid erection in male.