Understanding the Current Knowledge Gaps and the Future Perspective of COVID-19 Infections: A Rapid Review of Literature
Keywords:
Coronavirus, COVID-19, SARS-CoV-2
Abstract
The outbreak of the novel SARS-CoV-2, the virus that causes COVID-19 has remained a serious public health challenge. The high infectivity and mortalities associated with SAS-CoV-2 infections compared to other known viruses of the same group have necessitated the introduction of various prevention guidelines which may have the potential of affecting all spheres of human life. Efforts to better understand the new virus, prevent the spread and reduce its impacts on humans, have spurred very rapid scientific research and publications among experts. The volume of these scientific publications and the rate at which new knowledge is evolving may pose some difficulties for people to stay abreast with the trend of these discoveries. This rapid article review addressed this at this critical time, and keep the readers, researchers, and policymakers updated on the rapidly emerging research findings. Although the world is still struggling with the fourth wave and newly emerging variants, efforts have started yielding significant results in reducing community transmission and mortalities associated with COVID-19 infection.
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References
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Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020 Feb 15;395(10223):507-13.https://doi.org/10.1016/S0140-6736 (20)30211-7
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WHO. 2020a. “WHO Coronavirus Disease (COVID-19) Dashboard.” World Health Organization. Retrieved June 28, 2020. https://covid19.who.int/.
Liu Y, Yan LM, Wan L, et al. Viral dynamics in mild and severe cases of COVID-19. The Lancet Infectious Diseases. 2020 June; 20(6): 656-7. https://doi.org/10.1016/S1473-3099(20)30232-2
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Patel SK, Velkoska E, and Burrell LM. Emerging markers in cardiovascular disease: Where does angiotensin‐converting enzyme 2 fit in?. Clinical and Experimental Pharmacology and Physiology. 2013 Aug;40(8):551-9. https://doi.org/10.1111/1440-1681.12069
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Wenham C, Smith J, and Morgan R. COVID-19: the gendered impacts of the outbreak. The Lancet. 2020 Mar 14;395(10227):846-8.https://doi.org/10.1016/S0140-6736(20)30526-2
Yuki K, Fujiogi M,and Koutsogiannaki S. COVID-19 pathophysiology: A review. Clinical immunology. 2020 Apr 20:108427.https://doi.org/10.1016/j.clim.2020.108427
Malik YA. Properties of Coronavirus and SARS-CoV-2. The Malaysian Journal of Pathology. 2020 Apr 1;42(1):3-11. http://mjpath.org.my/2020/v42n1/properties-of-coronavirus.pdf
Zhou, P., Yang, X., Wang, X. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579, 270–3 (2020). https://doi.org/10.1038/s41586-020-2012-7
Ruan Q, Yang K, Wang W, Jiang L, and Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive care medicine. 2020 May;46(5):846-8.https://doi.org/10.1007/s00134-020-06028-z
Letko, M., Marzi, A. & Munster, V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nature Microbiol 5, 562–9 (2020). https://doi.org/10.1038/s41564-020-0688-y
Walls AC, Park YJ, Tortorici MA, et al. Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein. Cell. 2020; 181:2. 281-92.e6 https://doi.org/10.1016/j.cell.2020.02.058
Jeffers SA, Tusell SM, Gillim-Ross L, et al. CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proceedings of the National Academy of Sciences. 2004;101(44):15748-53.https://doi.org/10.1073/pnas.0403812101
Mizumoto K, Kagaya K, Zarebski A, and Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Eurosurveillance. 2020; 25(10):2000180.https://doi.org/10.2807/1560-7917.ES.2020.25.10.2000180
Sahin AR, Erdogan A, Agaoglu PM, et al. 2019 novel coronavirus (COVID-19) outbreak: a review of the current literature. EJMO. 2020;4(1):1-7. DOI: 10.14744/ejmo.2020.12220
Iwalokun BA, Olalekan A, Adenipekun E, et al. Improving the Understanding of Immunopathogenesis of Lymphopenia as a Correlate of SARS-COV-2 Infection Risk and Disease Progression in African Patients: UGLY SARS-COV-2 Study Protocol.Jmir 2020; 21242. https://doi.org/10.2196/preprints.21242
Yonggang Zhou, Binqing Fu, et al. Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients, National Science Review, Volume 7, Issue 6, June 2020, Pages 998–1002, https://doi.org/10.1093/nsr/nwaa041
Shi H, Han X, Jiang N, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. The Lancet Infectious Diseases. 2020; 20(4):425-34.https://doi.org/10.1016/S1473-3099(20)30086-4.
Ai T, Yang Z, Hou H, et al. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology. 2020:200642.https://doi.org/10.1148/radiol.2020200642
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet. 2020;395(10223):497-506.https://doi.org/10.1016/S0140-6736(20)30183-5.
Chuan Qin, Luoqi Zhou, Ziwei Hu, et al. Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China, Clinical Infectious Diseases, , ciaa248. https://doi.org/10.1093/cid/ciaa248
Zhang F, Abudayyeh OO, and Gootenberg JS. A protocol for detection of COVID-19 using CRISPR diagnostics. A protocol for detection of COVID-19 using CRISPR diagnostics. 2020;8.https://go.idtdna.com/rs/400-UEU-432/images/Zhang%20et%20al.%2C%202020%20COVID-19%20detection%20%28updated%29.pdf
Di L, Fu Y, Sun Y, et al. RNA sequencing by direct tagmentation of RNA/DNA hybrids. Proceedings of the National Academy of Sciences. 2020;117(6):2886-93.https://doi.org/10.1073/pnas.1919800117
WHO. 2020b. “WHO Welcomes Preliminary Results about Dexamethasone Use in Treating Critically Ill COVID-19 Patients.” World Health Organization. July 10, 2020 https://www.who.int/news-room/detail/16-06-2020-who-welcomes-preliminary-results-about-dexamethasone-use-in-treating-critically-ill-covid-19-patient.
Gebrie D, Getnet D, and Manyazewal T. Efficacy of remdesivir in patients with COVID-19: a protocol for systematic review and meta-analysis of randomised controlled trials. BMJ Open. 2020;10(6):e039159. doi: 10.1136/bmjopen-2020-039159
Lin TY, Chang WJ, Hsu CY, et al. Impacts of remdesivir on dynamics and efficacy stratified by the severity of COVID-19: a simulated two-arm controlled study. medRxiv. 2020; 5(17): 20104711. doi: https://doi.org/10.1101/2020.05.17.20104711.
Cortegiani A, Ingoglia G, Ippolito M, Giarratano A, and Einav S. A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19. Journal of critical care. 2020:57. 279-83.https://doi.org/10.1016/j.jcrc.2020.03.005
Gao J, Tian Z, and Yang X. Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies. Bioscience trends. 2020; 14(1): 72-3. https://doi.org/10.5582/bst.2020.01047
Published
2022-10-14
How to Cite
C.Okpua, N. (2022). Understanding the Current Knowledge Gaps and the Future Perspective of COVID-19 Infections: A Rapid Review of Literature. GPH-International Journal of Biological & Medicine Science, 5(10), 01-10. https://doi.org/10.5281/zenodo.7329245
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Copyright (c) 2022 Nelson C. Okpua
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